Workshop 2: January 16, 2026 - Gestational Trophoblastic Disease and Neoplasia: Bridging Histopathology and Genetics
Pathologists working with obstetrical and gynecologic specimens often encounter a spectrum of trophoblastic proliferations. This workshop will provide the knowledge needed to distinguish entities ranging from hydatidiform moles to placental site and epithelioid trophoblastic tumors. Distinction of these entities from mimics and pathological variants like aneusomy, and twin or chimeric/mosaic moles can be facilitated by understanding trophoblast cell biology in normal human development and the impact of genetic errors, especially those in fertilization. Participants will refine their diagnostic approach to complex trophoblastic lesions and make more informed decisions when selecting ancillary testing.
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You may register for each workshop individually, or you may register for all four workshops at a bundled rate. If you would like to register for all four 2026 January Workshops at the bundled rate, please visit this link. Please note that course content will not become available until the date of each workshop. Recorded content will be posted within approximately one week after a live workshop. Click the "Register" tab to register.
Pricing Per Workshop
$150: Members
$200: Non-Members
$50: Trainees
Bundled Pricing (access to all 4 Workshops)
$550: Members
$700: Non-Members
$150: Trainees
The SPP offers pathologists located outside of 'high income' nations, as deemed by the World Health Organization, access to educational programs at 30% of full cost. To learn more and apply for a discount, click HERE.
Target Audience
The education design of this activity addresses the needs of physicians and scientists in the field of pediatric, perinatal and general pathology who are involved in the diagnosis and/or treatment of pediatric patients with pathologic disorders.
Learning Objectives
1. Understand the conceptual framework by which abnormal trophoblastic proliferations are classified. With this framework, learners will develop strategies to classify clinical cases more accurately and efficiently in the WHO schema.
2. Understand the developmental cell biology of trophoblasts. With this cell biological context, learners will be able to apply immunohistochemical analysis such as p63, CD146 and p57 immunostains as they phenotype abnormal trophoblast proliferations more confidently.
3. Explore the genetic mechanisms driving gestation trophoblastic disease and neoplasia. Leveraging these genetics insights will provide learners the ability to decide when genetic analysis of ploidy and parental origin is appropriate for diagnosis of trophoblastic disease.
4. Familiarize the learner with rare variants and mimics of gestational trophoblastic disease, so that they can more readily recognize important pitfalls like twin and chimeric/mosaic moles.
Available Credit
- 2.00 ABPATH Lifelong Learning
- 2.00 AMA PRA Category 1 Credit™
- 2.00 Participation Credit(s)

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